GRAIL Grabs $300 Million Ahead of Possible IPO on Hong Kong Exchange Published: May 22, 2018 By Alex Keown With a new chief executive officer on board , GRAIL, Inc. has secured a whopping $300 million in an oversubscribed Series C financing round led by multiple Chinese investment groups. When you want to screen asymptomatic patients for cancer, you would use a cancer blood test. MENLO PARK, Calif., Sept. 9, 2020 — GRAIL, Inc., a healthcare company whose mission is to detect cancer early, when it can be cured, today announced that it has filed a registration statement on Form S-1 with the Securities and Exchange Commission (SEC) for a proposed initial public offering of its common stock in the United States. Grail estimates that a 1% reduction in cancer mortality in the United States would be worth $695 billion in today’s dollars from increased quality of life, productivity, and survival. Investors include Jeff Bezos, Sequoia, Johnson & Johnson, Bill Gates, and Illumina, the largest shareholder in Grail at the moment with 98,310,709 shares or 14.6% of the company. See the SEC Form S-1 online at SEC here. Grail is a pre-revenue company, something we’re not overly keen on. These are just some of the interesting insights presented in the Grail S-1 that makes us all the more excited about our investment in Guardant. We’re also MBAs, which means we’re not really capable of doing much more than simple analysis anyways. Grail, the mon­strous­ly backed liq­uid biop­sy biotech, has filed for an IPO. And here we are today, poring over their S-1 filing as the Illumina-backed venture has just filed for an Initial Public Offering (IPO). Grail was formed within Illumina in 2015. Most cancers are diagnosed too late, predominantly because we lack recommended screening tests for most types of cancers, those which are responsible for 71% of cancer deaths. Sept 9 (Reuters) - U.S-based cancer testing startup Grail Inc, which has received funding from Amazon.com … Grail Stock. The company says their cash and IPO proceeds will get them through at least twelve months, but let’s say they have three years of runway if all that R&D spend shifts to marketing spend and they can keep a consistent burn rate. The San Francisco startup ended up taking in $2 billion in disclosed funding to further their mission to detect cancer early, when it can be cured. Molike Ashford of Genomeweb discusses the S-1 in a premium article here. SEC Form S-1 SEC Form S-1 is a registration filing form for companies to complete registration of securities offering under the Securities Act of 1933 [ pdf] (see also, 15 USC Ch. This act, also known as the Truth in Securites Act was inacted to bring greater transparency to securities. (not just the IPO) an ipo is still the holy grail ... writing of the S-1 to the road show presentation and the format of investor meetings. SLQT:: IPO price $20, peaked to $26 opening day and now down to $20. Your email address will not be published. 2A, Part 77. GRAIL is combining high-intensity sequencing, leading-edge computer science, and large population-scale clinical studies to develop a blood test for early-stage cancer detection. Since we’re long Guardant (GH) given their leadership position in what’s looking to be a $54 billion potential market for cancer blood testing, we want to see what threat Grail poses to Guardant. In the simplest of terms, we like growing green lines and shrinking blue lines – eventually. RPTX:: IPO price $20, opening day $30 and now at $30. EquityZen is a marketplace for shares of proven pre IPO tech companies. A simple analysis results in a simple conclusion. 9 Sep 20 Files SEC. Wasn’t even 48 hours ago that we were commenting on how one of Illumina’s big venture bets – Grail – didn’t seem to be doing much. See BioPharmaDive here. Now the good news is, even prior to the IPO here, this company has a ton of cash. Grail has no green lines – growing or otherwise – so we’re sticking with Guardant. Sustainable Development Acquisition I Corp. Dream Finders Homes, Inc, Dream Finders Homes, Inc. Clarim Acquisition Corp, Clarim Acquisition Corp. Jack Creek Investment Corp, Jack Creek Investment Corp. ComSovereign Holding Corp, ComSovereign Holding Corp. AzurRx BioPharma, Inc, AzurRx BioPharma, Inc. For patients with cancer, a liquid biopsy provides an alternative to a traditional biopsy. As reported on September 9, 2020, by BioPharmaDive, GRAIL has filed with the SEC for an IPO. Grail, the cancer detection start-up backed by tech giants Alphabet and Amazon, is already seeking new funding, mere months after it closed a $900 million round in March. Author: Sustainable Development Acquisition I Corp. Virtuoso Acquisition Corp, Virtuoso Acquisition Corp. ECP Environmental Growth Opportunities Corp. This represents 34.4 percent ownership of the company. That compares very favorably with $13.6 billion in gross proceeds from 59 SPAC IPOs … The company is looking to go public at a time that the Renaissance IPO ETF IPO, +0.78% has rallied 20.1% over the past three months, while the S&P 500 SPX, +1.39% has gained 3.9%. Save my name, email, and website in this browser for the next time I comment. PCVX:: IPO price $16, opening day $26 and still up at 40 today. Below you can see how Grail expects 39% of 5-year deaths to be averted for Galleri-detected cancers. Grail Merger Sub, Inc. discloses 34.40% activist ownership in GSB / GlobalSCAPE, Inc. 2020-07-28 - Grail Merger Sub, Inc. has filed an SC 13D form with the Securities and Exchange Commission (SEC) disclosing ownership of 6,468,511 shares of GlobalSCAPE, Inc. (US:GSB). Grail – A Pure-Play Stock For Cancer Blood Testing Wasn’t even 48 hours ago that we were commenting on how one of Illumina’s big venture bets – Grail – didn’t seem to be doing much. Blood-sampling device. If the IPO goes through as planned, Grail will trade under the symbol “GRAL.”. Shift4:: IPO price $23, first trade was at $33 and now sitting at 46.20. While both Guardant and Foundation Medicine (now part of Roche) received approvals for their liquid biopsy PMA applications last month, it’s important to clarify the differences between a liquid biopsy and a cancer blood test. Tags Biotech Louis Weiner Stanford University. These are just few. Grail spun out of Illumina in 2015 and has a long-term agreement that requires Grail to give a small percentage of its revenue, whenever it comes, to Illumina. Then there’s Guardant, a company that’s burning about $80 million a year with $522 million in cash on hand. After looking at Grail’s S-1 filing, we’re even more convinced that early cancer detection is a disruptive technology that we want to have exposure to, and Guardant fits the bill. The Illumina spinout expects to launch the product, Galleri, as a lab developed test (LDT) in 2021. FMTX:: IPO price $20, ended opening day at $39 and now sitting at $41. 13D/G Filings 2012. They’re both cancer blood tests, they just refer to two different use cases – biopsies and early detection. Required fields are marked *. Find out which tech stocks we love, like, and avoid in this special report, now available for all Nanalyze Premium annual subscribers. SEC Form S-1 is a registration filing form for companies to complete registration of securities offering under the Securities Act of 1933 [pdf] (see also, 15 USC Ch. That’s because traction is a demonstration of the critically important “product-market-fit” which shows you’ve built what your customers need and are capable of selling it at a price point that’s attractive to buyer and seller. While all of the markers were capable of detecting cancer, we found that methylation profiling yielded significantly better results for cancer detection. A rough estimation of burn rate for Grail is about $250 million a year and they have $685 million in cash on hand plus the $100 million they plan to raise in the IPO. Request Access. Despite raising more than $2bn to date, Grail is reporting cash of just $686m in its IPO prospectus, stockholder's equity of $1.3bn, and a cash burn of $139m in the first 6 months of 2020. It’s a simple analysis, but that’s because we like to adhere to the KISS principle whenever possible. If your product is selling like hotcakes, it’s much easier to raise funding. Title 17 of the Code of Federal Regulations. So far, from 99 SPAC IPOs, nearly $40 billion in gross proceeds was raised. Grail’s four foundational studies collectively enrolled around 115,000 participants which the company believes are the largest linked datasets of genomic and clinical data in the cancer field. Through form S-1, companies offering securites are required to disclose a description of the company’s properties and business; a description of the security being offered; information about management running the company and financial statements that have been certified by independent accountants. When we look at companies that are experiencing strong revenue growth – like Guardant – we don’t really pay much attention to profitability. Founded. In 2016, they received investments from third parties and began operating as a stand-alone company. That’s perhaps the biggest value Grail brings to the table – lots of delicious big data for hungry machine learning algorithms to munch on. ... Upsized record IPO, e-cigarette questions, a CEO Dance and more. GRAIL aims to develop a blood test to detect cancer early before symptoms appear offering higher survival rates compared to late-stage diagnosis. Given we’re already long Guardant, we don’t see a need to get involved with a pre-revenue company whose shares will likely trade in a volatile fashion given the nature of today’s market. What Grail has been spending their funding on is lots of pre-work to make sure they’re taking the right approach. View More Companies. Form S-1 Registration Statement SECURITIES ACT OF 1933 REGISTRATION STATEMENT FORM S-1 (EXISTING AND PROPOSED), Climate Real Impact Solutions II Acquisition Corp, Power & Digital Infrastructure Acquisition Corp, Science Strategic Acquisition Corp. Alpha. Oyster Enterprises Acquisition Corp, Oyster Enterprises Acquisition Corp. Z-Work Acquisition Corp, Z-Work Acquisition Corp. Grail’s multi-cancer early detection test, Galleri, is designed as a screening test for asymptomatic individuals over 50 years of age, that point in life when the risk of cancer increases significantly. This act, also known as the Truth in Securites Act was inacted to bring greater transparency to securities. Coverage at Stat-Plus (Subscription) here. October 08, 2018. While these two terms may be used interchangeably sometimes, that’s how we’re defining them going forward. Recent news which mentions Grail. Grail anticipates Galleri to become commercially available in 2021 as a laboratory developed test (LDT). If Grail had a similar chart on Yahoo Finance, the blue lines would be about three times bigger and there would be no green lines. Read Next G RAIL, a developer of next-gen cancer screening tests, filed on Wednesday with the SEC to raise up to $100 million in an initial public offering. Cloud copy here. And here we are today, poring over their S-1 filing as the Illumina-backed venture has just filed for an I nitial P ublic O ffering (IPO). “It also helps solve a core problem in detecting cancer early in asymptomatic individuals, which is the low level of cancer signal circulating in the blood,” says the company. Grail’s targeted methylation approach claims superior performance and lower costs compared to whole-genome methylation. Grail joins a flood of other tech IPO announcements this fall, including Snowflake, Sumo Logic, Unity, Asana, JFrog, and Palantir.. Pure-play disruptive tech stocks are not only hard to find, but investing in them is risky business. That comes later. They also have $1.4 billion in redeemable convertible stock. Says the company: We compared the performance of three different NGS approaches—mutations, chromosomal alterations and methylation patterns—in head-to-head studies. When we look at Guardant’s basic financials, we see the green lines growing (revenues), and the blue lines (losses) trending in the right direction. Latest News about Grail. Your email address will not be published. Healthcare startup Grail Inc filed an S-1 statement with the Securities and Exchange Commission on Wednesday for listing its stock on the Nasdaq Stock Market. 2A, Part 77. However, if you’re doing nothing but burning cash, that makes us nervous. A feed of the latest S-1 filings can be found below. Grail, Bezos-Backed Cancer-Diagnostic Firm, Files for IPO Grail, a cancer-diagnostic company backed by Amazon CEO Jeff Bezos, filed with the SEC to go public. September 21, 2020. The Menlo Park, CA company announced its IPO … Illumina (NASDAQ: ILMN) spinout Grail (GRAL) has filed a preliminary prospectus for a $100M IPO. While Grail has been perfecting their test, they’ve also managed to accumulate some very valuable big data. Montauk Renewables, Inc, Montauk Renewables, Inc. European Sustainable Growth Acquisition Corp. Dyne Therapeutics, Inc, Dyne Therapeutics, Inc. Qualtrics International Inc, Qualtrics International Inc. S-1 registration filings typically include information about the total number of shares offered and the price per share as well as Investment Prospectus information offered to investors. 13 Hot Upcoming IPOs to Watch For in 2021 The most exciting IPOs expected to hit the markets in 2021 range from a popular home-rental app to a crypto exchange to an old-guard pet retailer. $886 million in cash prior to the IPO. GRAL Grail S-1 2020 IPO registration. Grail’s early detection blood test, Galleri, has demonstrated in clinical studies the ability to detect more than 50 types of cancer, across all stages, and localize the cancer signal with a high degree of accuracy, from a single blood draw. The key thing to keep ... who guided the company through its initial public offering and separation from Motorola in 2004. The case for early screening is simple and compelling. Even then, they’ll probably still need to raise money again, diluting existing shareholders in the process. Grail CEO Jennifer Cook Grail on Wednesday filed with the U.S. Securities and Exchange Commission to raise up to $100 million in an initial public offering ahead of the anticipated launch of its multi-cancer liquid biopsy screening test for use in asymptomatic individuals. A dds details from IPO filing, background. The … Buy or sell Grail stock pre IPO via an EquityZen fund. They then plan to submit a premarket approval application (PMA) of a subsequent version of Galleri in as early as 2023. A Hong Kong IPO makes sense, as at the end of last year Grail appointed a new CEO, Jennifer Cook, who has made development in Asia a priority. An IPO is Still the Holy Grail ... A successful initial public offering sets the stage for the company's first years as a public company, not only providing access to public capital markets, but also establishing the governance structure and finance processes that will support it … Aims to raise $100M during IPO. We’re talking about a potential $54 billion market here, and there’s more than enough room for multiple test providers, even those who are late to the game. EquityZen is a marketplace for shares of proven pre IPO tech companies. Illumina buying cancer-screening spinout Grail in blockbuster $8B biotech deal. The security will be listed under the symbol “GRAL.” Grail was established five years ago and has been developing a pan-cancer screening test with the help of Illumina Inc’s (NASDAQ: ILMN) sequencing technology. Cancer diagnostic specialist Grail today filed for an initial public offering (IPO) on the Nasdaq, with the stock to trade under the ticker symbol GRAL. 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